Is 250 cholesterol too high?

Oct 22, 2026

A total cholesterol reading of 250 mg/dL (about 6.45 mmol/L) falls in the “high” category. General guidelines classify total cholesterol below 200 mg/dL as desirable, 200–239 mg/dL as borderline high, and 240 mg/dL or above as high.

However, the total number alone does not tell the full story. Your doctor will look more closely at LDL (“bad”) cholesterol, HDL (“good”) cholesterol, and triglycerides, because LDL is the main driver of plaque buildup in arteries.

What the numbers mean

Test Generally desirable level
Total cholesterol Below 200 mg/dL ncbi.nlm.nih
LDL cholesterol Below 100 mg/dL ncbi.nlm.nih
HDL cholesterol At least 40 mg/dL for men; at least 50 mg/dL for women medicalnewstoday
Triglycerides Below 150 mg/dL medicalnewstoday

If your LDL is 250 mg/dL, that is very high and needs prompt medical attention. But if your total cholesterol is 250 mg/dL because of high HDL, the risk interpretation can be different.

What you can do

  • Ask for a full lipid profile if you only know the total cholesterol number.

  • Eat more fiber-rich foods such as beans, oats, vegetables, fruits, nuts, and whole grains.

  • Reduce refined carbohydrates, sugary foods, deep-fried foods, and excess saturated fat.

  • Include regular movement, such as brisk walking, cycling, yoga, or strength training.

  • Avoid smoking and manage blood pressure, weight, and blood sugar.

  • Follow your doctor’s advice on whether lifestyle changes alone are enough or medication is needed.

High cholesterol often has no symptoms, so a reading of 250 mg/dL should not be ignored—even if you feel completely well.medicalnewstoday